Dermatomyositis is a group of connective tissue disorderds characterized by non-suppurative inflammation of the skeletal muscle and skin lesion. It is associated with malignancy, especially of the stomach, lung, overy and breast. We report a case
of
dermatomyositis with uterine cervical concer. A 78 year old female patient was admitted because of progressive proximal muscle weakness, skin rashes, and vaginal spotting. She was bedridden because of severe proximal muscle weakness and atrophy,
unable
to elevate her head, and suffered from dysphagia. Gottron's patches were found on the knuckles of the hands, scaly erythematous rashes on the extensor surfaces of bilateral elbows, wrists and kness. The serum concentrations of musfcle enzymes
were
elevated, the biopsy of quadriceps muscle showed the features compatable with myositis, and the uterine cervical biopsy revealed squamous cell careinoma, which was determined to be in stage IIb by pelvic CT. Radiotherapy(total 3240 cGy) was done
for the
cervical cancer and prednisolone(initially 60mg/day) was given for the dermatomyositis. The muscle power improved only a little although the concentrations of serum muscle enzmes returned to normal. She deceased of aspiration pneumonia 43 days
after the
admission.
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